H E Shannon Selected Research

ameltolide

12/2008

Nonlinear mixed effects pharmacokinetic/pharmacodynamic analysis of the anticonvulsant ameltolide (LY201116) in a canine seizure model.

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H E Shannon Research Topics

Disease

2	Epilepsy (Aura) 12/2008 - 01/2005
2	Seizures (Absence Seizure) 12/2008 - 01/2005
2	Shock 12/2007 - 03/2004
2	Alzheimer Disease (Alzheimer's Disease) 04/2001 - 05/2000
2	Neuralgia (Stump Neuralgia) 09/2000 - 07/2000
2	Hyperalgesia 09/2000 - 07/2000
2	Pain (Aches) 09/2000 - 07/2000
1	Tremor (Tremors) 04/2001
1	Hypothermia 04/2001
1	Cocaine-Related Disorders (Cocaine Addiction) 08/2000
1	Schizophrenia (Dementia Praecox) 05/2000
1	Catalepsy 05/2000

Drug/Important Bio-Agent (IBA)

3	Pilocarpine (Ocusert)FDA LinkGeneric 01/2005 - 09/2000
3	Muscarinic AgonistsIBA 04/2001 - 09/2000
3	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 09/2000 - 05/2000
2	Kainic Acid (Kainate)IBA 01/2005 - 03/2004
2	Pentylenetetrazole (Metrazol)IBA 01/2005 - 03/2004
2	Antipsychotic Agents (Antipsychotics)IBA 04/2001 - 05/2000
2	xanomelineIBA 04/2001 - 05/2000
2	Pertussis ToxinIBA 09/2000 - 07/2000
1	ameltolideIBA 12/2008
1	Anticonvulsants (Antiepileptic Drugs)IBA 12/2008
1	Phenobarbital (Luminal)FDA Link 12/2007
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2005
1	ConvulsantsIBA 03/2004
1	Aminophylline (Carine)FDA LinkGeneric 03/2004
1	Nicotine FDA Link 03/2004
1	4-Aminopyridine (4 Aminopyridine)FDA Link 03/2004
1	N-Methylaspartate (NMDA)IBA 03/2004
1	StrychnineIBA 03/2004
1	BicucullineIBA 03/2004
1	PicrotoxinIBA 03/2004
1	ParasympathomimeticsIBA 04/2001
1	Muscarinic M4 ReceptorIBA 04/2001
1	Tacrine (Cognex)FDA Link 09/2000
1	OxotremorineIBA 09/2000
1	PhysostigmineIBA 09/2000
1	Proteins (Proteins, Gene)FDA Link 09/2000
1	Cholinergic ReceptorsIBA 09/2000
1	LY 297802 (vedaclidine)IBA 09/2000
1	Cholinergic Agents (Cholinergics)IBA 09/2000
1	Fentanyl (Sublimaze)FDA LinkGeneric 07/2000
1	Desipramine (Pertofrane)FDA LinkGeneric 07/2000
1	Lidocaine (Xylocaine)FDA LinkGeneric 07/2000
1	Morphine (MS Contin)FDA LinkGeneric 07/2000
1	Oxymetazoline FDA Link 07/2000
1	Clonidine (ST 155)FDA LinkGeneric 07/2000
1	Carbamazepine (Tegretol)FDA LinkGeneric 07/2000
1	Opioid Analgesics (Opioids)IBA 07/2000
1	Dizocilpine Maleate (Dizocilpine)IBA 07/2000
1	Gi-Go GTP-Binding Protein alpha Subunits (Gi alpha Subunit)IBA 07/2000
1	Olanzapine (Zyprexa)FDA Link 05/2000
1	Haloperidol (Haldol)FDA LinkGeneric 05/2000
1	Clozapine (Clozaril)FDA LinkGeneric 05/2000
1	Dopamine AntagonistsIBA 05/2000

Therapy/Procedure

1	Therapeutics 12/2008
1	Spinal Injections 07/2000